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Function and mechanisms in defence strategies
1ETH Zürich, Institute of Integrative Biology (IBZ), Universitätsstrasse 16, CH-8092 Zürich, Switzerland.
Abstract:
A useful discussion of defence strategies cannot do without linking defence mechanisms to their function, that is, their contributions to fitness. Whereas the former is the domain of immunology, the latter is the subject of evolutionary ecology. For this, the concepts of the defence chart and the disease space can be used to connect the two domains and to sharpen the focus. These use different approaches but converge to the same end, that is, to understand what fitness costs and benefits are associated with existing mechanisms and how to identify the best defence strategy in a given environment.
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