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A Systematic Review and Meta-Analysis of 12-Month Patency After Intervention for Iliofemoral Obstruction Using

Ghulam M Majeed1, Krishan Lodhia1, Jemima Carter1

  • 1Academic Department of Vascular Surgery, St. Thomas' Hospital, School of Cardiovascular Medicine & Sciences, King's College London, London, UK.

Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists
|November 11, 2021
PubMed

Insights

Dedicated venous stents show comparable 1-year effectiveness for iliofemoral outflow obstruction in non-thrombotic iliac vein lesions and post-thrombotic syndrome. Further research is needed due to study heterogeneity.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiology

Background:

  • Symptomatic iliofemoral outflow obstruction is a condition affecting deep venous system.
  • Endovascular stenting is a proposed treatment for this condition.
  • Dedicated venous stents have been developed to improve treatment outcomes.

Purpose of the Study:

  • To systematically review and meta-analyze the effectiveness of dedicated venous stents.
  • To compare outcomes at 1-year post-intervention.
  • To evaluate treatment for non-thrombotic iliac vein lesions (NIVL), acute deep vein thrombosis (DVT), and post-thrombotic syndrome (PTS).

Main Methods:

  • Systematic review and meta-analysis of 49 studies.
  • Included 5154 patients with NIVL, DVT, or PTS.
  • Extracted data on technical success, 1-year stent patency, and symptom relief.

Main Results:

  • High technical success rates (97%-100%) with low complication rates.
  • 1-year primary patency rates: NIVL (96%), DVT (91%), PTS (77-78%).
  • Significant symptom improvement reported for venous claudication and ulcer healing in NIVL and PTS patients.

Conclusions:

  • First-generation dedicated venous stents demonstrate comparable 1-year patency and clinical outcomes to non-dedicated stents for NIVL and PTS.
  • Significant heterogeneity among studies necessitates standardized reporting criteria for deep venous stenting outcomes.
Abstract

Keywords:
DVTnitinol stentstentthrombosisvenous occlusion

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