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Building research capacity in India: The Masters in Clinical Research program at the Tata Memorial Centre

Durga Gadgil1, Manju Sengar2, C S Pramesh3

  • 1Research Consultant, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.

Perspectives in Clinical Research
|November 11, 2021
PubMed

Keywords:
Researchresearch activityresearch personnel

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Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...