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Impact of Adherence, Patient Perception, and Knowledge to Statin Therapy - A Cross-Sectional Study
Siddhi Umarje1, Neha M James1, Priti Dave2
1Department of Clinical Pharmacy, Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.
Indian Journal of Endocrinology and Metabolism
|November 11, 2021
Summary
Statin adherence in India is suboptimal, with 42.30% showing good adherence. Patient knowledge, perception, and factors like cost significantly impact adherence to statin therapy for cardiovascular disease risk factors.
Area of Science:
- Cardiology
- Pharmacoeconomics
- Public Health
Background:
- Cardiovascular diseases, diabetes, and hyperlipidemia are prevalent in India.
- High statin utilization necessitates adherence assessment for effective treatment outcomes.
- Statin adherence in the Indian population remains understudied.
Purpose of the Study:
- To measure statin therapy adherence among Indian patients.
- To assess patient knowledge and perception regarding statin therapy.
- To identify barriers and facilitators of statin adherence in India.
Main Methods:
- A cross-sectional observational study was conducted.
- 130 individuals visiting a tertiary care hospital participated.
- A systematically developed interview questionnaire assessed knowledge, perception, and adherence.
Main Results:
- Good adherence was observed in 42.30% of patients.
- Females, patients with coronary heart disease history, and those on atorvastatin (monotherapy or fixed-dose combination) showed better adherence.
- Lack of knowledge, cost, refill issues, and adverse effects were identified as adherence barriers.
Conclusions:
- Patient knowledge and perception are crucial for statin adherence.
- Coronary heart disease history, statin choice, and cost influence adherence.
- Patient counseling and improving cost-effectiveness are potential strategies to enhance statin adherence.
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