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A comparative cross-sectional analysis on outcomes of Covid-19 patients requiring dialysis

Chinmay N Gokhale1, Smita S Chavhan1, Harshal N Mahajan2

  • 1Community Medicine, HBTMC and RNCH, Mumbai, Maharashtra, India.

Journal of Family Medicine and Primary Care
|November 11, 2021
PubMed

Insights

COVID-19 patients requiring hemodialysis faced higher mortality rates compared to those not needing dialysis. Advancing age, diabetes, and intensive care needs were key predictors of death in this vulnerable group.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Coronavirus Disease 2019 (COVID-19) pandemic declared March 2020.
  • COVID-19 disproportionately impacts patients with comorbidities, especially those on dialysis.
  • Patients requiring renal replacement therapy, like intermittent hemodialysis, are prone to severe COVID-19 clinical states.

Purpose of the Study:

  • To compare outcomes of COVID-19 patients requiring hemodialysis versus those not requiring hemodialysis.
  • To identify risk factors for mortality in COVID-19 patients undergoing dialysis.

Main Methods:

  • Cross-sectional observational study conducted April-August 2020.
  • Included 271 COVID-19 patients requiring hemodialysis and 271 matched controls.
  • Age and sex matching used for control group selection.

Main Results:

  • 18.8% mortality in hemodialysis patients versus 8.9% in controls.
  • 10.3% of hemodialysis patients required intensive care.
  • Advancing age, need for intensive care, and diabetes were significant predictors of mortality.

Conclusions:

  • Hemodialysis patients experienced higher mortality rates from COVID-19.
  • Advancing age, diabetes, and intensive care unit (ICU) admission are significant mortality predictors.
  • The study highlights the critical impact of the COVID-19 pandemic on dialysis patients.
Abstract

Keywords:
Covid-19hemodialysisodds for mortality

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