Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Necrotizing enterocolitis: a 15-year experience.

G M Leong, J H Drew

    The Australian & New Zealand Journal of Obstetrics & Gynaecology
    |February 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Parental pre-pregnancy BMI is a dominant early-life risk factor influencing BMI of offspring in adulthood.

    Obesity science & practice·2016
    Same author

    Endotracheal tube management in newborn infants with hyaline membrane disease.

    The Australian journal of physiotherapy·2014
    Same author

    Clinical studies on morphine; the effect of morphine upon the circulation of man and upon the circulatory and respiratory responses to tilting.

    Anesthesiology·2010
    Same author

    Studies on nutrition; the effect of preoperative force-feeding on surgical patients.

    Annals of surgery·2010
    Same author

    A nutritional study of neurosurgical patients; with special reference to nitrogen balance and convalescence in the postoperative period.

    Journal of neurosurgery·2010
    Same author

    The Ski proto-oncogene regulates body composition and suppresses lipogenesis.

    International journal of obesity (2005)·2009
    Same journal

    Determining the Feasibility of a No-Ultrasound Screening Tool for Early Medical Abortion in Australia.

    The Australian & New Zealand journal of obstetrics & gynaecology·2026
    Same journal

    'All In': Equitable Health Outcomes Require Culturally Safe Care for Everybody.

    The Australian & New Zealand journal of obstetrics & gynaecology·2026
    Same journal

    Benzylpenicillin Concentrations in Intrapartum Group B Streptococcus Prevention Guidelines; A Systematic Review of the Evidence.

    The Australian & New Zealand journal of obstetrics & gynaecology·2026
    Same journal

    Retrospective Cohort Study of Foetal Growth Restricted Births After 40 Weeks at an Australian Tertiary Maternity Hospital Between 2018 and 2021.

    The Australian & New Zealand journal of obstetrics & gynaecology·2026
    Same journal

    Models of Antenatal Care for Rural Indigenous Women: A Systematic Review.

    The Australian & New Zealand journal of obstetrics & gynaecology·2026
    Same journal

    Dispensing of Antiemetics During Pregnancy in Aotearoa New Zealand, 2005-2020.

    The Australian & New Zealand journal of obstetrics & gynaecology·2026
    See all related articles

    Necrotizing enterocolitis (NEC) affected 87 infants, with a 26.4% mortality rate. This study highlights an increasing incidence of NEC and identifies associated risk factors in mothers and infants, including low birth weight.

    Area of Science:

    • Neonatalogy
    • Pediatric Surgery
    • Obstetrics

    Background:

    • Necrotizing enterocolitis (NEC) is a significant cause of neonatal mortality.
    • Understanding NEC incidence and risk factors is crucial for improving infant outcomes.
    • Previous studies have indicated associations between NEC and prematurity, but further investigation into obstetric risk factors is warranted.

    Purpose of the Study:

    • To analyze the incidence, mortality, and risk factors associated with necrotizing enterocolitis (NEC) in infants over a 15-year period.
    • To identify maternal and infant characteristics that increase the risk of developing NEC.
    • To describe the treatment modalities and sequelae of NEC in a neonatal population.

    Main Methods:

    • Retrospective analysis of 87 infants diagnosed with NEC between 1971 and 1985 at Mercy Maternity Hospital, Melbourne.

    Related Experiment Videos

  • Data collection included infant birth weight, gestational age, maternal risk factors (gestational diabetes, pre-existing diabetes, estriol excretion), and treatment outcomes.
  • Statistical analysis was performed to determine incidence rates, mortality, and associations between risk factors and NEC development.

    • Main Results:

    • The incidence of NEC increased from 0.07% to 0.25% of livebirths during the study period.
    • A significant association was found between NEC and higher-risk obstetric populations, including gestational diabetes and subnormal estriol excretion.
    • Very low birth weight (VLBW) infants (<1500g) comprised 29.9% of NEC cases, with a mean age of onset of 9.9 days.
    • The overall mortality rate for NEC was 26.4%, contributing 2.6% to all neonatal deaths.
    • Colonic strictures, fistulas, and short-gut syndrome were observed sequelae in survivors.

    Conclusions:

    • The incidence of NEC is increasing, necessitating continued surveillance and research into preventative strategies.
    • Maternal risk factors, such as gestational diabetes, play a significant role in NEC development.
    • Early identification of high-risk infants and prompt medical or surgical intervention are essential for managing NEC and reducing mortality.