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[The challenges of managing thoracic pain in cystic fibrosis (CF)]

A T Hoffmann1, S Dillenhöfer1, T Lücke1

  • 1Universitätsklinik für Kinder- und Jugendmedizin, Ruhr-Universität Bochum, Alexandrinenstraße 5, 44791, Bochum, Deutschland.

Schmerz (Berlin, Germany)
|November 11, 2021
PubMed

Insights

Pain management in cystic fibrosis (CF) is underestimated. Current German guidelines lack pain management protocols, necessitating an interdisciplinary approach for effective thoracic pain relief in CF patients.

Area of Science:

  • Medical research
  • Pulmonology
  • Pain management

Background:

  • Cystic Fibrosis (CF) is a rare genetic disorder causing progressive multi-systemic complications.
  • Pain is a frequently underestimated symptom in CF patients, impacting quality of life.
  • Abdominal and pulmonary involvement are characteristic, often exacerbating pain experiences.

Approach:

  • A comprehensive literature review of existing guidelines and scientific publications on pain management in CF was conducted.
  • Clinical findings from a young CF patient experiencing progressive thoracic pain were integrated.
  • The review focused on identifying gaps in current pain management strategies within CF care.

Key Points:

  • German CF guidelines do not currently address the diagnosis and management of pain.
  • International studies indicate a correlation between pain intensity and mortality in CF.
  • Data on the efficacy of specific pain management interventions in CF are limited.
  • Managing pain in CF presents unique challenges due to multi-organ involvement.

Conclusions:

  • Pain management in CF necessitates meticulous monitoring and an interdisciplinary strategy.
  • Recommendations for treating thoracic pain in CF are proposed.
  • The complexity of organ involvement in CF complicates the use of both opioid and non-opioid analgesics.
  • Opioid therapy in CF patients requires close medical supervision due to risks like hypoxia and opioid-induced constipation (OIC).
Abstract

Keywords:
Adverse eventChildrenEpidural catetherHypoxiaOpioids

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