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Assessment of Vascular Function in Patients With Chronic Kidney Disease
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Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

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Visceral adiposity indicators and cardiovascular risk in hemodialytic patients

Dejane de Almeida Melo1, Alcione Miranda Dos Santos2, Elane Viana Hortegal Furtado3

  • 1Programa de Pós-graduação em Nutrição, Universidade Federal de Pernambuco, Recife, PE, Brasil, dejane.melo.res@ufpe.br.

Archives of Endocrinology and Metabolism
|November 11, 2021
PubMed

Insights

The hypertriglyceridemia-waist phenotype (HWP) and visceral adiposity index (VAI) are common in hemodialysis patients. HWP showed stronger associations with multiple cardiometabolic risk factors, especially in females.

Area of Science:

  • Nephrology
  • Cardiology
  • Endocrinology

Background:

  • Cardiovascular diseases are the leading cause of mortality in chronic kidney disease (CKD) patients undergoing hemodialysis (HD).
  • Identifying reliable markers for cardiometabolic risk (CR) is crucial for this high-risk population.
  • The hypertriglyceridemia-waist phenotype (HWP) and visceral adiposity index (VAI) are emerging indicators of metabolic dysfunction.

Purpose of the Study:

  • To determine the prevalence of HWP and VAI in patients with CKD on hemodialysis.
  • To assess the association between HWP and VAI with various cardiometabolic risk factors in this cohort.

Main Methods:

  • A cross-sectional study involving 265 hemodialysis patients in northeastern Brazil.
  • VAI calculated using BMI, waist circumference, triglycerides, and HDL-c.
  • HWP defined by elevated waist circumference and triglycerides.
  • Poisson regression analysis used to identify associations with cardiometabolic risk factors.

Main Results:

  • Prevalence of HWP was 29.82% and VAI was 58.49%.
  • VAI was associated with female gender and high body fat percentage.
  • HWP demonstrated associations with female gender, alcohol consumption, obesity, high body fat percentage, and reduced HDL-c.

Conclusions:

  • The hypertriglyceridemia-waist phenotype (HWP) is associated with a greater number of cardiometabolic risk factors compared to VAI in hemodialysis patients.
  • HWP emerges as a valuable tool for monitoring cardiometabolic risk, particularly in female hemodialysis patients.
Abstract

Keywords:
Chronic renal insufficiencyadipositycardiovascular diseases

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