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WITHDRAWN: lncRNA Linc00173 modulates glucose metabolism and multidrug chemoresistance in SCLC: Potential molecular

Shuyu Wang1, Fanrui Zeng2, Shumei Liang3

  • 1Department of Pathology, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510282, People's Republic of China; Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510282, People's Republic of China.

Molecular Therapy : the Journal of the American Society of Gene Therapy
|November 11, 2021
PubMed

Insights

This study has been withdrawn due to duplicated images in western blots, raising concerns about the scientific integrity of the findings. The editor-in-chief lost faith in the results presented.

Area of Science:

  • Scientific publishing
  • Research integrity
  • Biomedical research

Background:

  • Concerns regarding image duplication in scientific publications.
  • The importance of adhering to ethical standards in research reporting.

Purpose of the Study:

  • To address allegations of image duplication in a published article.
  • To investigate potential scientific misconduct and its impact on research findings.

Main Methods:

  • Editor-in-chief initiated a review following discovery of image duplication.
  • Analysis of western blot images in Figures 1I, 1J, 3F, S5B, and S6B.
  • Authors provided explanation regarding file management errors.

Main Results:

  • Evidence of duplicated western blot images was identified.
  • The editor-in-chief expressed a loss of confidence in the study's findings.
  • Authors claimed the duplications were unintentional errors that do not impact conclusions.

Conclusions:

  • The article has been officially withdrawn from publication.
  • The editor-in-chief's decision was based on compromised research integrity.
  • Further investigation into image manipulation in scientific research is warranted.
Keywords:
Linc00173YB1glucose metabolismin vitroin vivolong noncoding RNAmolecular mechanismsmultidrug resistancesmall cell lung cancertherapeutic targetstissue samples

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