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Updated: Oct 13, 2025

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
Published on: April 13, 2022
[Research progress on organoids in stomatology]
1School of Stomatology, Zunyi Medical University, Special Key Laboratory of Oral Diseases Research, Higher Education Institution in Guizhou Province, Zunyi Key Laboratory of Oral Diseases Research, Zunyi 563000, China.
Abstract:
The organoid is a kind of distinctive micro-organ formed by stem cells with the ability of self-renewal, which can be cultured in three-dimensional scaffold in vitro. With the development of cell culture system, organoids have been gradually applied in researches such as in vitro organ model establishment, drug testing and even the repairing or replacing damage organs. It shows significantly promising prospects. This review article aims to summarize the latest research progress and provide the theoretical foundation and prospects for the development of organoids in stomatology.

