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Periarticular plasma cell tumors in cats
Linden E Craig1, Danielle E Lieske2
1University of Tennessee, Knoxville, TN, USA.
Veterinary Pathology
|November 12, 2021
Summary
Periarticular plasma cell tumors with amyloid in cats often affect the tarsus and can be aggressive. Diagnosis is challenging due to abundant amyloid and low cellularity, with a median survival of 194 days.
Area of Science:
- Veterinary Pathology
- Oncology
Background:
- Periarticular plasma cell tumors are rare in cats.
- Amyloid deposition can be a feature of these feline tumors.
- Canine cutaneous plasma cell tumors are generally benign, unlike their feline counterparts.
Purpose of the Study:
- To describe the clinicopathologic features of periarticular plasma cell tumors with abundant amyloid in cats.
- To evaluate the behavior and prognosis of these feline tumors.
Main Methods:
- Retrospective case series analysis of 11 feline cases.
- Review of clinical records, histopathology, and staging information.
- Survival data analysis for cases with follow-up.
Main Results:
- The tarsus was the most common site (10/11 cases).
- Tumors involved dermis, subcutis, and sometimes synovium and bone (lysis).
- Median survival was 194 days; 4 cases metastasized.
Conclusions:
- Feline periarticular plasma cell tumors with amyloid can be aggressive, involving deeper tissues.
- Diagnosis can be difficult due to low cellularity and high amyloid content.
- These tumors have a poorer prognosis compared to canine cutaneous plasma cell tumors.
