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Classification of diabetic retinopathy using unlabeled data and knowledge distillation
Sajjad Abbasi1, Mohsen Hajabdollahi1, Pejman Khadivi2
1Department of Electrical and Computer Engineering, Isfahan University of Technology, 84156-8311, Iran.
Artificial Intelligence in Medicine
|November 12, 2021
Summary
This study introduces a novel method for transferring knowledge from large AI models to smaller ones, even with limited labeled medical images. This approach enhances diagnostic capabilities in areas like diabetic retinopathy detection.
Area of Science:
- Artificial Intelligence
- Machine Learning
- Medical Imaging
Background:
- Machine Learning (ML) and Artificial Intelligence (AI) show promise in healthcare diagnostics.
- Limited labeled medical data hinders the effectiveness of ML models like Convolutional Neural Networks (CNNs).
- Transfer Learning and Knowledge Distillation offer ways to reuse models but have limitations, especially regarding architectural similarity and complete knowledge transfer.
Purpose of the Study:
- To propose a novel knowledge distillation approach combined with transfer learning.
- To enable the complete knowledge transfer from a large model to a smaller one.
- To leverage unlabeled data for enhanced knowledge transfer in medical image analysis.
Main Methods:
- A new knowledge distillation technique is introduced, integrating transfer learning principles.
- The method utilizes unlabeled data in an unsupervised manner to maximize knowledge transfer.
- The approach aims to distill the complete knowledge from a source model to a target smaller model.
Main Results:
- The proposed method effectively transfers knowledge from complex models to lighter ones.
- Performance of smaller models significantly improved when using unlabeled data and knowledge distillation.
- The approach demonstrated effectiveness in classifying diabetic retinopathy images using public datasets (Messidor, EyePACS).
Conclusions:
- The novel approach successfully addresses the challenge of scarce labeled data in medical imaging.
- It enables efficient knowledge transfer, enhancing the utility of smaller AI models for diagnostics.
- This method holds significant potential for improving AI-driven medical image analysis, particularly for conditions like diabetic retinopathy.

