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Non-compaction cardiomyopathy, Becker muscular dystrophy, neuropathy and recurrent syncope
Love Shah1, Ingrid Tam2, Shravan Nosib3
1Internal Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
BMJ Case Reports
|November 12, 2021
Summary
Becker muscular dystrophy can cause heart failure due to left ventricular non-compaction cardiomyopathy. Early diagnosis is crucial for managing this rare condition in patients with neuromuscular syndromes.
Area of Science:
- Cardiology
- Neurology
- Genetics
Background:
- Left ventricular non-compaction cardiomyopathy (LVNC) is a rare congenital heart defect.
- Becker muscular dystrophy (BMD) is an X-linked recessive neuromuscular disorder.
Observation:
- A 50-year-old man presented with new heart failure symptoms.
- Cardiac imaging revealed left ventricular non-compaction cardiomyopathy.
- The patient also exhibited muscular weakness, leading to a diagnosis of Becker muscular dystrophy.
Findings:
- This case highlights the association between left ventricular non-compaction cardiomyopathy and Becker muscular dystrophy.
- Dystrophinopathy, the underlying genetic cause of BMD, can lead to cardiac involvement.
- Comprehensive diagnostic workup is essential for identifying rare cardiomyopathies in neuromuscular conditions.
Implications:
- Consider rare cardiomyopathies in patients with neuromuscular syndromes, and vice versa.
- Early recognition and management of cardiac complications in dystrophinopathies can improve patient outcomes.
- This case underscores the importance of multidisciplinary approaches in diagnosing and managing complex genetic disorders.
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