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Cherubism: report of three cases.

ASDC Journal of Dentistry for Children

|July 1, 1987

Summary

Cherubism is a rare, inherited autosomal-dominant disorder primarily affecting the mandible, causing painless bilateral swelling. This condition leads to jaw expansion and potential displacement of teeth.

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Area of Science:

Genetics
Oral and Maxillofacial Surgery
Pediatric Dentistry

Background:

Cherubism is an inherited autosomal-dominant condition.
It primarily affects the mandible, presenting as jaw swelling.

Observation:

Patients typically present with painless bilateral swelling at the mandibular angles.
Lesions are hard on palpation, causing jaw expansion.

Findings:

The disease causes significant mandibular enlargement.
Erupted teeth may be displaced due to the expanding lesions.

Implications:

Early diagnosis and management are crucial for preventing complications.
Understanding the genetic basis aids in diagnosis and potential therapeutic strategies.