Tissue Analysis of Lung-Targeted Delivery of siRNA and Plasmid DNA
Kaido Kurrikoff1, Birgit Vunk2, Ülo Langel2,3
1Institute of Technology, University of Tartu, Tartu, Estonia. kaido.kurrikoff@ut.ee.
Methods in Molecular Biology (Clifton, N.J.)
|November 12, 2021
Abstract:
Development of nucleic acid delivery systems requires the use of adequate tissue analysis methods, especially when aiming tissue-targeted drug delivery. In this chapter, a protocol is presented for analyzing a reporter signal from the lung tissue. Because lung is an important target tissue from the clinical point of view, yet represents a challenge from the histological point of view, this protocol can be used in any lung-targeting drug delivery project.
