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Efficacy of diphenhydramine hydrochloride for local anesthesia before oral surgery
Journal of the American Dental Association (1939)
|August 1, 1987
Abstract:
The efficacy of diphenhydramine hydrochloride with epinephrine was tested against lidocaine with epinephrine in a double-blind study. Patients with allergic reactions to general local anesthetics were safely and effectively treated with diphenhydramine hydrochloride as an anesthetic alternative.