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Updated: Oct 13, 2025

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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
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Advanced human mucosal tissue models are needed to improve preclinical testing of vaccines
David Komla Kessie1, Thomas Rudel1
1Chair of Microbiology, Biocenter of the University of Würzburg, Würzburg, Germany.
Plos Biology
|November 12, 2021
Abstract:
Many vaccine candidates with promising results in preclinical testing fail in human trials. New complex human tissue models have the potential to improve the predictability of vaccine safety and efficacy in human clinical trials.

