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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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Updated: Oct 13, 2025

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
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Lockdown Effect on Elderly Nutritional Health.

Jeyniver Ghanem1,2, Bruno Colicchio2, Emmanuel Andrès1,3

  • 1Faculté de Médecine, Université de Strasbourg, 4 Rue Kirschleger, FR-67085 Strasbourg, France.

Journal of Clinical Medicine
|November 13, 2021
PubMed
Summary
This summary is machine-generated.

Lockdowns significantly worsened nutritional health in home-dwelling elderly individuals, increasing malnutrition rates. Social isolation emerged as the primary driver of these negative health impacts during confinement.

Keywords:
COVID-19SARS-CoV-2bodyweightelderlylockdownmalnutrition

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Area of Science:

  • Gerontology
  • Public Health
  • Nutritional Science

Background:

  • Pandemics and associated lockdowns can lead to unintended health consequences.
  • Previous reports have documented malnutrition in COVID-19 patients.
  • The impact of lockdowns on the nutritional status of non-COVID-19 elderly individuals receiving home care is less understood.

Purpose of the Study:

  • To assess the short-term effects of lockdown measures on the nutritional health of elderly individuals living at home.
  • To identify changes in nutritional parameters and key contributing factors in this population.

Main Methods:

  • Study involved 50 elderly subjects with stable weight, BMI, and MNA scores prior to lockdown.
  • Nutritional parameters were reassessed after the lockdown period.
  • Factors contributing to malnutrition were analyzed.

Main Results:

  • Significant alterations in weight, body mass index, and MNA scores were observed post-lockdown.
  • Malnutrition prevalence increased from 28-34% to 58%.
  • Social isolation was identified as the primary trigger for malnutrition, accounting for 64% of negative effects.

Conclusions:

  • The lockdown rapidly and significantly impacted the nutritional status of elderly individuals living at home, even without direct COVID-19 infection.
  • Social isolation and depressive syndromes were the main factors contributing to malnutrition.
  • Findings can inform public health strategies for future confinement scenarios to mitigate adverse effects on the elderly.