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Updated: Oct 13, 2025

Author Spotlight: Investigating mRNA Spatial Distribution in Drosophila Muscle Tissue
Published on: September 8, 2023
Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration
Karolina Archacka1, Maria A Ciemerych1, Anita Florkowska1
1Department of Cytology, Institute of Developmental Biology and Biomedical Sciences, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02-096 Warsaw, Poland.
Abstract:
miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We present selected miRNAs and lncRNAs that have been shown to control myogenic differentiation and show that manipulation of their levels could be used to improve myogenic differentiation of various types of stem and progenitor cells. Finally, we discuss how physical activity affects miRNA and lncRNA expression and how it affects muscle well-being.
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