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Updated: Oct 13, 2025
08:17
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
11.1K
Systemic Review: Ozone: A Potential New Chemotherapy
Jose Baeza-Noci1, Rosa Pinto-Bonilla1
1Department of Human Anatomy & Embryology, School of Medicine, University of Valencia, 46010 Valencia, Spain.
International Journal of Molecular Sciences
|November 13, 2021
Summary
Ozone gas shows preclinical promise against cancer cells, but clinical success remains distant. Further research and expert guidance are needed to bridge this gap for effective cancer treatment.
Area of Science:
- Oncology
- Medical Chemistry
- Biomedical Research
Background:
- Sixty years of research indicate ozone gas's positive preclinical effects on cancer cells.
- Despite promising preclinical data, ozone therapy has not translated into successful clinical cancer treatments.
Purpose of the Study:
- To review existing evidence on ozone gas's efficacy in cancer.
- To identify necessary comprehensive approaches for clinical translation.
- To suggest future research directions for oncologists and researchers.
Main Methods:
- Comprehensive literature review of preclinical and clinical studies on ozone gas in oncology.
- Analysis of barriers to clinical translation.
- Identification of potential research avenues.
Main Results:
- Consistent preclinical evidence supports ozone's anti-cancer properties.
- Significant challenges hinder the clinical application of ozone therapy.
- A multidisciplinary approach involving medical specialists is crucial.
Conclusions:
- Ozone gas demonstrates potential as an anti-cancer agent based on preclinical data.
- Translating these findings to clinical practice requires overcoming significant hurdles.
- Further targeted research, guided by experts, is essential to realize ozone's therapeutic potential in oncology.
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