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Related Concept Videos

Cancer Therapies02:49

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Systemic Review: Ozone: A Potential New Chemotherapy.

Jose Baeza-Noci1, Rosa Pinto-Bonilla1

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International Journal of Molecular Sciences
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Ozone gas shows preclinical promise against cancer cells, but clinical success remains distant. Further research and expert guidance are needed to bridge this gap for effective cancer treatment.

Keywords:
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Area of Science:

  • Oncology
  • Medical Chemistry
  • Biomedical Research

Background:

  • Sixty years of research indicate ozone gas's positive preclinical effects on cancer cells.
  • Despite promising preclinical data, ozone therapy has not translated into successful clinical cancer treatments.

Purpose of the Study:

  • To review existing evidence on ozone gas's efficacy in cancer.
  • To identify necessary comprehensive approaches for clinical translation.
  • To suggest future research directions for oncologists and researchers.

Main Methods:

  • Comprehensive literature review of preclinical and clinical studies on ozone gas in oncology.
  • Analysis of barriers to clinical translation.
  • Identification of potential research avenues.

Main Results:

  • Consistent preclinical evidence supports ozone's anti-cancer properties.
  • Significant challenges hinder the clinical application of ozone therapy.
  • A multidisciplinary approach involving medical specialists is crucial.

Conclusions:

  • Ozone gas demonstrates potential as an anti-cancer agent based on preclinical data.
  • Translating these findings to clinical practice requires overcoming significant hurdles.
  • Further targeted research, guided by experts, is essential to realize ozone's therapeutic potential in oncology.