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Updated: Oct 13, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Identification of COVID-19 Waves: Considerations for Research and Policy
Andrés Ayala1, Pablo Villalobos Dintrans2, Felipe Elorrieta1
1Departamento de Matemática y Ciencia de la Computación, Facultad de Ciencias, Universidad de Santiago, Santiago 9170022, Chile.
Abstract:
The identification of COVID-19 waves is a matter of the utmost importance, both for research and decision making. This study uses COVID-19 information from the 52 municipalities of the Metropolitan Region, Chile, and presents a quantitative method-based on weekly accumulated incidence rates-to define COVID-19 waves. We explore three different criteria to define the duration of a wave, and performed a sensitivity analysis using multivariate linear models to show their commonalities and differences. The results show that, compared to a benchmark definition (a 100-day wave), the estimations using longer periods of study are worse in terms of the model's overall fit (adjusted R2). The article shows that defining a COVID-19 wave is not necessarily simple, and has consequences when performing data analysis. The results highlight the need to adopt well-defined and well-justified definitions for COVID-19 waves, since these methodological choices can have an impact in research and policy making.
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