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Updated: Oct 13, 2025

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
Passive Vaping from Sub-Ohm Electronic Cigarette Devices
Maurizio Manigrasso1, Carmela Protano2, Matteo Vitali2
1Department of Technological Innovations, National Institute for Insurance against Accidents at Work (INAIL), 00187 Rome, Italy.
Sub-ohm electronic cigarette (e-cig) aerosol emissions vary with e-liquid composition and atomizer power. Higher heat fluxes can lead to increased volume concentrations and formation of larger droplets, impacting passive vaping exposure.
Area of Science:
- Environmental Health
- Aerosol Science
- Combustion Science
Background:
- Sub-ohm electronic cigarettes (e-cigs) are increasingly popular.
- Understanding passive vaping exposure is crucial for public health.
- Previous studies have not fully characterized aerosol emissions from high-power e-cigs.
Purpose of the Study:
- To investigate passive vaping aerosol emissions from sub-ohm e-cigs.
- To analyze the influence of e-liquid composition (vegetable glycerin/propylene glycol ratio, nicotine content) and atomizer power on aerosol characteristics.
- To determine the relevance of different aerosol metrics for assessing second-hand exposure.
Main Methods:
- Volunteer vaping sessions were conducted to measure aerosol number size distribution (6 nm-10 µm).
- Two atomizer types (double-coil and octa-coil) with varying power settings (25-150 W) and heat fluxes (130-398 kW m-2) were used.
- E-liquids with different vegetable glycerin (VG)/propylene glycol (PG) ratios (50/50 and 80/20) and nicotine content were tested.
Main Results:
- Lower particle number concentrations (NTot) were observed for nicotine-containing e-liquids at low heat flux.
- At higher heat fluxes, NTot decreased while volume concentrations increased significantly due to super-micron droplet formation.
- Higher volume concentrations were associated with the 80/20 VG/PG liquid due to VG vaporization and decomposition.
- Increasing power in the double-coil atomizer led to reduced volume concentrations for both liquids.
- Two main modes (1 and 2 µm) were observed in volume size distributions, indicating the emission of condensable decomposition products.
Conclusions:
- Aerosol emissions from sub-ohm e-cigs are complex and depend on vaping parameters.
- Volume concentration is a critical metric for assessing passive vaping exposure due to the formation of larger aerosols.
- The study highlights the need to consider e-liquid composition and high power settings when evaluating e-cig aerosol risks.
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10:44Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
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