[Participation of leukocytes in primary hemostasis]

Introduction of a hemolysate of erythrocytes and ADP in the plasma containing leucocytes and platelets results in the formation of mixed-cell (leucocytic-thrombocytic) aggregates, aggregation rate depending on the number of leucocytes involved. In healthy donors this process is ensured equally by both cell types. In inflammation and especially in chronic myelocytic leukemia leucocytes play the main role in mixed-cell aggregation. Aggregate formation in such patients is characterized by a high intensity which may be related with an increase in total function of pathological leucocytes.