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Updated: Oct 13, 2025

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
[Coronary angiography my false friend].
1Service de Cardiologie, Hôpital Gabriel Montpied, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France.
Coronary angiography remains essential for diagnosing and treating ischemic heart disease, despite its invasive nature. Advanced imaging and complementary techniques improve its diagnostic accuracy for coronary artery disease.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Coronary angiography, first performed in 1958, is a cornerstone in diagnosing and treating ischemic heart disease, with over 400,000 procedures annually in France.
- Despite advancements in imaging and simplification of techniques, coronary angiography is invasive, involves radiation, and uses potentially nephrotoxic contrast agents.
- It provides a 2D projection of dynamic coronary arteries, requiring technical perfection and careful analysis to mitigate inherent limitations.
Purpose of the Study:
- To review the current role and limitations of coronary angiography in the diagnosis and treatment of coronary artery disease.
- To highlight the importance of complementary functional (FFR, IMR) and morphological (IVUS, OCT) techniques in interpreting angiographic findings.
- To assess the place of coronary angiography in relation to emerging non-invasive methods like coroscanner.
Main Methods:
- Review of historical development and current practices of coronary angiography.
- Discussion of imaging advancements and technical considerations.
- Analysis of limitations and the role of adjunctive diagnostic tools.
Main Results:
- Coronary angiography, while invasive, offers crucial diagnostic and interventional capabilities for coronary artery disease.
- Complementary techniques like FFR, IMR, IVUS, and OCT are vital for resolving ambiguities and guiding treatment decisions.
- Non-invasive methods like coroscanner have limitations (resolution, calcification artifacts) that often necessitate angiography.
Conclusions:
- Coronary angiography remains indispensable for diagnosing coronary artery disease and guiding revascularization strategies.
- Awareness of its pitfalls and integration with complementary functional and morphological assessments are critical for optimal patient care.
- Despite ongoing development of non-invasive alternatives, coronary angiography's established role persists due to its comprehensive diagnostic and therapeutic utility.
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