Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Geroprotective Agents, Including Glucagon-Like Peptide-1 Receptor Agonists, for Ocular Health.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics·2026

Same author

Clinical Features and Prognostic Factors in Pediatric Open Globe Injuries.

Journal of pediatric ophthalmology and strabismus·2026

Same author

Disruption of the gut microbiota in regulator of G protein signaling 14 knockout (RGS14 KO) mice alters the metabolome and reduces enhanced exercise capacity.

European journal of applied physiology·2026

Same author

Metformin Use and Risk of Glaucoma: A Systematic Review and Meta-Analysis.

American journal of ophthalmology·2026

Same author

Evaluation of Social Media Short-Form Video Content for Patient Education on Vision-Threatening Diseases.

Journal of ophthalmology·2026

Same author

Outpatient visits and secondary surgeries following open globe injuries: a single institution retrospective analysis.

International ophthalmology·2026

Search research articles

Related Experiment Video

Updated: Oct 13, 2025

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

Appositional Choroidal Detachment Following XEN45 Gel Stent Requiring Surgical Drainage.

Yash S Shah¹, Marko Oydanich¹, Rajen U Desai²

¹Department of Ophthalmology & Visual Science, Rutgers New Jersey Medical School, Newark.

Journal of Glaucoma

|November 13, 2021

Summary

Severe choroidal detachments can complicate XEN45 glaucoma surgery. This case highlights the need for prompt intervention, including explantation and drainage, to restore vision after XEN45 device implantation.

More Related Videos

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Related Experiment Videos

Last Updated: Oct 13, 2025

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Area of Science:

Ophthalmology
Glaucoma Surgery
Microsurgery

Background:

Severe primary open-angle glaucoma (POAG) often requires surgical intervention when maximal medical therapy fails.
The XEN45 aqueous drainage device is a minimally invasive option for glaucoma management.
Ab externo implantation is a surgical technique for device placement.

Observation:

An 82-year-old male with severe POAG underwent uneventful XEN45 implantation.
Postoperatively, the patient developed significant choroidal detachments with vision loss.
Initial medical management with steroids and cycloplegia was insufficient.

Findings:

The choroidal detachments became appositional, necessitating intervention.
Xen explantation and surgical drainage of the choroidal detachment were performed.
Post-surgical intervention led to improved visual acuity.

Implications:

Significant choroidal detachments are a potential complication of XEN45 implantation.
Prompt surgical management may be required for vision recovery.
This case underscores the importance of monitoring for and managing choroidal effusions after glaucoma device surgery.