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Postprocedural Radial Artery Compression Time In Chronic AnticoaguLated patients using StatSeal: The PRACTICAL-SEAL

Rodrigo Bagur1, Luiz F Ybarra1, Zeev Israeli2

  • 1London Health Sciences Centre, London, Ontario, Canada.

International Journal of Cardiology
|November 14, 2021
PubMed

Insights

The StatSeal® disc effectively achieves hemostasis in patients undergoing transradial coronary angiography on uninterrupted oral anticoagulation therapy. This adjunct hemostasis method demonstrated short times to complete hemostasis without increased bleeding risk.

Area of Science:

  • Cardiology
  • Vascular Access
  • Hemostasis

Background:

  • Patients on chronic oral anticoagulation (OAC) therapy face high bleeding risks during cardiac catheterization.
  • Transradial coronary angiography necessitates effective hemostasis strategies for patients on OAC.

Purpose of the Study:

  • To evaluate the safety and efficacy of the StatSeal® disc for adjunct hemostasis.
  • To assess hemostasis times in patients undergoing transradial coronary angiography under uninterrupted OAC therapy.

Main Methods:

  • A study included 180 patients undergoing transradial cardiac catheterization without OAC interruption.
  • Patients received periprocedural unfractionated heparin (UFH).
  • The StatSeal® disc was used for adjunct hemostasis.

Main Results:

  • Complete hemostasis was achieved in 71.1 ± 13.0 minutes.
  • Patients on novel oral anticoagulants (NOACs) showed shorter hemostasis times compared to warfarin users.
  • No significant differences in bleeding events or radial artery occlusion were observed.

Conclusions:

  • The StatSeal® disc provides effective adjunct hemostasis in patients on uninterrupted OAC therapy.
  • The use of StatSeal® is associated with short times to complete hemostasis.
  • This method is safe and effective for transradial coronary angiography in OAC patients.
Abstract

Keywords:
AngiographyAnticoagulationPercutaneous coronary interventionRadial access

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