"Uncontrolled" Hypertension Is Not an Independent Risk Factor for Adverse Short-Term Outcomes Following Total Joint...

Uncontrolled hypertension (HTN) is a risk factor for mortality following elective surgery and poor hemodynamic control during total joint arthroplasty (TJA). However, the relationship between uncontrolled HTN and TJA outcomes remains poorly understood. The purpose of this study is to better define HTN parameters that are predictive of adverse arthroplasty outcomes.

This is a retrospective cohort analysis on patients who underwent primary TJA for osteoarthritis between 2017 and 2021 at a large orthopedic practice. Uncontrolled HTN was defined as a systolic blood pressure (SBP) > 140 mm Hg, or diastolic blood pressure (DBP) > 90 mm Hg. Spearman's rank correlations were used to evaluate relationships among uncontrolled HTN and operative duration, hemoglobin drop, allogenic transfusions, length of stay, intraoperative/postoperative complications, and readmissions.

Four thousand three hundred forty-five patients met the selection criteria, of which 55.1% (N = 2394) presented with uncontrolled HTN. In total, 17.1% (N = 745) and 3.2% (N = 138) of patients had an SBP ≥ 160 and 180 mm Hg, respectively. In addition, 1.9% of patients (N = 84) presented with SBP ≥ 200 mm Hg (N = 13) and/or DBP ≥ 100 mm Hg (N = 71). Eight-four percent (N = 626) of patients who presented with SBP > 160 mm Hg had been preoperatively prescribed HTN control medications. Receiver operator curve analysis demonstrated poor predictive value of blood pressure for all aforementioned outcome variables.

Our findings suggest that as defined, uncontrolled HTN is not an appropriate individual predictor of TJA outcomes and should not be used as a "hard stop" when determining eligibility for elective surgery. Further research utilizing a larger cohort is needed to define the relationship between HTN and TJA outcomes.