Related Experiment Video
Updated: Oct 13, 2025
10:49
Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
8.9K
A major decrease in viral acute gastroenteritis in hospitalized Finnish children as rotavirus returns as the most
Oskari Pitkänen1, Jukka Markkula1, Maria Hemming-Harlo2
1Vaccine Research Centre, Tampere University, Arvo Ylpön katu 34, 33014 Tampere, Finland.
Summary
Rotavirus, norovirus, and sapovirus prevalence in children
Area of Science:
- Pediatric infectious diseases
- Virology
- Public health surveillance
Background:
- Rotavirus vaccination began in 2009.
- Previous surveillance data from 2006-2014 is available.
- This study assesses viral gastroenteritis in children.
Purpose of the Study:
- To determine the prevalence and genotypes of rotavirus, norovirus, and sapovirus in children.
- To compare current findings with historical surveillance data.
- To evaluate the impact of rotavirus vaccination on viral gastroenteritis patterns.
Main Methods:
- Stool samples collected from children (<16 years) with acute gastroenteritis (2017-2018).
- Analysis using reverse transcription PCR and sequencing.
- Comparison with surveillance data from 2006-2014.
Main Results:
- Rotavirus detected in 32%, norovirus in 27%, and sapovirus in 6.3% of samples.
- Rotavirus G9P[8] and G12P[8] were most common genotypes.
- Norovirus GII.4 accounted for 96% of norovirus detections.
Conclusions:
- All-cause acute gastroenteritis prevalence decreased significantly post-vaccination.
- Rotavirus is again the leading cause, but at low levels.
- No major changes in norovirus and sapovirus genotypes observed.
