Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

795
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
795
Drug Dependence01:17

Drug Dependence

1.2K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.2K
Specialized Care Centers and Settings-II01:30

Specialized Care Centers and Settings-II

795
Rural Health Centers
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
795
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

238
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
238
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

563
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
563
Drug Therapy01:28

Drug Therapy

117
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
117

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ASAM Consensus Standards for Substance Use Disorder Care Capabilities in Hospitals and Emergency Departments.

Journal of addiction medicine·2026
Same author

Medical Scribe and Ambient Artificial Intelligence Impact on Emergency Physician Documentation Burden and Clinical Productivity.

Annals of emergency medicine·2026
Same author

Abortion Politics: Physician Mobilization in the Wake of the Dobbs Decision.

Journal of health politics, policy and law·2026
Same author

Development and psychometric evaluation of the Liver Disease Stigma Scale (LDSS).

JHEP reports : innovation in hepatology·2026
Same author

Comparative Evaluation of Machine Translation Accuracy of Emergency Department Discharge Instructions: A Non-Inferiority Study.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine·2026
Same author

Performance of a Sepsis Prediction Model Across Different Sepsis Definitions.

JAMA network open·2026

Related Experiment Video

Updated: Oct 13, 2025

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
09:29

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Published on: August 4, 2022

2.3K

Nudging Emergency Department-Initiated Addiction Treatment.

Kelley Butler1, Tyler Chavez, Sarah Wakeman

  • 1From the Department of Family and Community Medicine, University of California San Francisco, Zuckerberg San Francisco General Hospital, San Francisco, CA (KB), Harvard Medical School, Boston, MA (TC), Substance Use Disorders Initiative, Massachusetts General Hospital and Harvard Medical School, Boston, MA (SW), ideas42 (TR, JL, JB, L-SK, JL), Department of Emergency Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA (SD, BH, BW, AR, AM).

Journal of Addiction Medicine
|November 14, 2021
PubMed
Summary
This summary is machine-generated.

Implementing behavioral science interventions in the Emergency Department (ED) significantly increased medication for addiction treatment (MAT) for opioid use disorder (OUD). This approach enhances OUD treatment initiation and engagement in the ED setting.

More Related Videos

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
09:16

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

15.4K
A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

9.9K

Related Experiment Videos

Last Updated: Oct 13, 2025

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
09:29

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Published on: August 4, 2022

2.3K
A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
09:16

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

15.4K
A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

9.9K

Area of Science:

  • Addiction Medicine
  • Behavioral Science
  • Emergency Medicine

Background:

  • Medication for addiction treatment (MAT) with buprenorphine initiated in the Emergency Department (ED) improves patient outcomes and reduces reliance on inpatient services.
  • Despite proven benefits, ED-initiated MAT for opioid use disorder (OUD) is not yet standard practice.
  • Barriers to physician adoption of MAT protocols in the ED setting require targeted interventions.

Purpose of the Study:

  • To assess the impact of a multipart, behavioral science-based intervention on increasing OUD-related treatments prescribed in the ED.
  • To identify and address key barriers to physician utilization of an ED-initiated MAT protocol.

Main Methods:

  • A campaign was launched to help ED faculty obtain the DEA-X waiver necessary for buprenorphine prescription.
  • Two ED-initiated buprenorphine treatment pathways were implemented.
  • A two-stage qualitative process informed by behavioral science identified physician barriers, leading to the development of four targeted behavioral interventions.
  • A regression discontinuity in time approach was used to estimate the causal effect of these interventions on daily OUD treatments.

Main Results:

  • The interventions led to an overall increase in OUD-related treatments in the ED, primarily driven by greater use of ambulatory referral orders.
  • Unadjusted analysis showed an increase of 0.80 OUD treatments per day post-intervention (P = 0.039), with ambulatory referrals increasing by 0.82 per day (P < 0.001).
  • The four-part intervention model demonstrated a causal effect, increasing daily opioid treatments in the ED by 1.6 per day (P = 0.045).

Conclusions:

  • A combination of patient-facing and provider-facing behavioral science interventions effectively increased the likelihood of ED providers offering MAT to patients with OUD.
  • These interventions support ED protocols and enhance the provision of ED-initiated MAT.
  • The findings highlight the potential of behavioral science to overcome barriers and integrate OUD treatment into emergency care settings.