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Published on: January 28, 2020
Current Status of Primary, Secondary, and Tertiary Prevention of Coronary Artery Disease
1Department of Physiology (APP), College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Insights
Preventive healthcare is crucial for combating coronary artery disease (CAD). Early identification and modification of risk factors like dyslipidemia and hypertension can prevent, slow, or reverse CAD progression.
Area of Science:
- Cardiology
- Preventive Medicine
- Public Health
Background:
- Coronary artery disease (CAD) accounts for 50% of cardiovascular disease deaths.
- Early identification and intervention are key to preventing CAD mortality.
- Atherosclerosis and plaque rupture are central to CAD development.
Purpose of the Study:
- To define primary, secondary, and tertiary prevention strategies for CAD.
- To explore the mechanisms of risk factor-induced atherosclerosis.
- To discuss the application of CAD risk scores and guidelines in prevention.
Main Methods:
- Review of CAD pathogenesis and risk factors.
- Definition and categorization of prevention strategies (primary, secondary, tertiary).
- Discussion of CAD risk assessment tools and clinical guidelines.
Main Results:
- Identified modifiable risk factors for CAD including dyslipidemia, diabetes, hypertension, smoking, obesity, and others.
- Described the role of risk factor modification in preventing and managing CAD.
- Highlighted the utility of CAD risk scores for targeting primary prevention efforts.
Conclusions:
- Modification of risk factors and adherence to prevention guidelines can prevent, regress, and slow CAD progression.
- Implementing these strategies improves patient quality of life.
- Effective CAD prevention reduces overall healthcare costs.
Abstract:
Fifty percent of all death from cardiovascular diseases is due to coronary artery disease (CAD). This is avoidable if early identification is made. Preventive health care has a major role in the fight against CAD. Atherosclerosis and atherosclerotic plaque rupture are involved in the development of CAD. Modifiable risk factors for CAD are dyslipidemia, diabetes, hypertension, cigarette smoking, obesity, chronic renal disease, chronic infection, high C-reactive protein, and hyperhomocysteinemia. CAD can be prevented by modification of risk factors. This paper defines the primary, secondary, and tertiary prevention of CAD. It discusses the mechanism of risk factor-induced atherosclerosis. This paper describes the CAD risk score and its use in the selection of individuals for primary prevention of CAD. Guidelines for primary, secondary, and tertiary prevention of CAD have been described. Modification of risk factors and use of guidelines for prevention of CAD would prevent, regress, and slow down the progression of CAD, improve the quality of life of patient, and reduce the health care cost.
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