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Updated: Oct 13, 2025

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process
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A Time-Course-Based Estimation of the Human Medial Olivocochlear Reflex Function Using Clicks.

Sriram Boothalingam1,2, Shawn S Goodman3, Hilary MacCrae4

  • 1Department of Communication Sciences and Disorders, University of Wisconsin-Madison, Madison, WI, United States.

Frontiers in Neuroscience
|November 15, 2021
PubMed
Summary

A new method uses click-trains to measure the medial olivocochlear reflex (MOCR) bilaterally in humans, assessing both its strength and speed. This advances auditory efferent system research and clinical applications.

Keywords:
click-evoked otoacoustic emissionskineticsmedial olivocochlear reflexmiddle ear muscle reflextime-course

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Area of Science:

  • Auditory Neuroscience
  • Otoacoustic Emissions
  • Human Auditory Physiology

Background:

  • The medial olivocochlear reflex (MOCR) plays a role in auditory processing and disorders.
  • Current clinical methods for MOCR assessment are limited, assaying only contralateral pathways and lacking kinetic information.

Purpose of the Study:

  • To develop and validate a novel method for concurrently assessing bilateral MOCR activity and kinetics in humans.
  • To overcome limitations of conventional MOCR assessment techniques.

Main Methods:

  • Repurposed otoacoustic emission (OAE)-evoking click-trains to simultaneously elicit and measure bilateral MOCR.
  • Presented click-trains at 80 dB peSPL at 62.5 Hz in 13 young normal-hearing adults.

Main Results:

  • Demonstrated the feasibility of the novel click-train method for assessing MOCR.
  • Obtained mean MOCR magnitude of 1.7 dB and activation time-constant of 0.2 s, consistent with prior reports.
  • Showcased potential for monitoring middle ear muscle reflex (MEMR) and obtaining MOCR kinetics.

Conclusions:

  • The developed click-train method offers a more comprehensive assessment of the MOCR in humans.
  • This technique allows for bilateral MOCR evaluation, including magnitude, kinetics, and MEMR monitoring.
  • The method provides visual and statistical confirmation of MOCR activation, enhancing clinical utility.