Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Two-Dimensional Microscopy in Microbiology01:29

Two-Dimensional Microscopy in Microbiology

699
Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
699
Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

435
Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...
435

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated Flavoromics and Metabolomics Reveal Aroma and Bioactive Characteristics of Six Mainstream Citri Reticulatae Pericarpium Cultivars.

Foods (Basel, Switzerland)·2026
Same author

Brain Cortex Thinning in Cardiac Allograft Vasculopathy　- Associations With Myocardial Fibrosis and Cognitive Impairment.

Circulation journal : official journal of the Japanese Circulation Society·2026
Same author

Strong phylogenetic signal from chloroplast genomes of three Barringtonia species provides the first genomic resources for their conservation.

BMC plant biology·2026
Same author

Microstructural MRI combined with metabolic MRI to evaluate the progression-free survival of patients with glioblastoma at the early follow-up after tumor treating fields: a pilot study.

BMC medical imaging·2026
Same author

The effectiveness of a real-world smoking cessation clinic: A prospective cohort study.

Tobacco induced diseases·2026
Same author

MYOD1 mutation drives cancer stem cell pathways and therapy-resistance in spindle cell/sclerosing rhabdomyosarcoma.

Nature communications·2026
Same journal

Novel variants in LSS related hypotrichosis simplex 14.

Frontiers in genetics·2026
Same journal

Network-based analysis identifies shared mechanisms between ischemic stroke and myocardial infarction and therapeutic ingredients of Buyang Huanwu Decoction.

Frontiers in genetics·2026
Same journal

GWAS analysis of a depression cohort defined by an EHR-phenotyping algorithm reveals the role of immune regulations in depression risk.

Frontiers in genetics·2026
Same journal

Ferroptosis, lipid metabolism, and genetic regulation in postoperative rehabilitation of elderly hip fractures: from molecular mechanisms to clinical translation.

Frontiers in genetics·2026
Same journal

Single-cell and pseudobulk analyses reveal hidden mitochondrial expression imbalance in gastric cancer.

Frontiers in genetics·2026
Same journal

Transcriptomic profiling and experimental validation of myeloid-cell-differentiation-related key genes in osteoarthritis.

Frontiers in genetics·2026
See all related articles

Related Experiment Video

Updated: Oct 13, 2025

Author Spotlight: High-Resolution 4D Light-Sheet Imaging and Virtual Reality in Zebrafish for Single-Cell Analysis of Heart Function
07:07

Author Spotlight: High-Resolution 4D Light-Sheet Imaging and Virtual Reality in Zebrafish for Single-Cell Analysis of Heart Function

Published on: January 5, 2024

1.5K

singlecellVR: Interactive Visualization of Single-Cell Data in Virtual Reality.

David F Stein1,2, Huidong Chen3,4,5,6, Michael E Vinyard3,4,5,6,7

  • 1Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Frontiers in Genetics
|November 15, 2021
PubMed
Summary
This summary is machine-generated.

We developed singlecellVR, a user-friendly web app for visualizing single-cell data using affordable virtual reality hardware. This tool makes complex single-cell data analysis accessible to more researchers.

Keywords:
VRclusteringdata visualizationscATAC-seqscRNA-seqsingle-celltrajectory inferencevirtual reality

More Related Videos

An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice
08:59

An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice

Published on: March 3, 2023

2.3K
Leveraging Virtual Reality for Immersive Segmentation and Analysis of Cryo-Electron Tomography Data
07:17

Leveraging Virtual Reality for Immersive Segmentation and Analysis of Cryo-Electron Tomography Data

Published on: January 24, 2025

1.1K

Related Experiment Videos

Last Updated: Oct 13, 2025

Author Spotlight: High-Resolution 4D Light-Sheet Imaging and Virtual Reality in Zebrafish for Single-Cell Analysis of Heart Function
07:07

Author Spotlight: High-Resolution 4D Light-Sheet Imaging and Virtual Reality in Zebrafish for Single-Cell Analysis of Heart Function

Published on: January 5, 2024

1.5K
An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice
08:59

An Open-Source Virtual Reality System for the Measurement of Spatial Learning in Head-Restrained Mice

Published on: March 3, 2023

2.3K
Leveraging Virtual Reality for Immersive Segmentation and Analysis of Cryo-Electron Tomography Data
07:17

Leveraging Virtual Reality for Immersive Segmentation and Analysis of Cryo-Electron Tomography Data

Published on: January 24, 2025

1.1K

Area of Science:

  • Computational Biology
  • Bioinformatics
  • Data Visualization

Background:

  • Single-cell assays enable modeling of cellular heterogeneity.
  • Advancements in single-cell assays necessitate innovative computational and visualization methods.
  • Virtual Reality (VR) offers dynamic data exploration but faces adoption barriers in single-cell research.

Purpose of the Study:

  • To present singlecellVR, a user-friendly web application for single-cell data visualization.
  • To enable visualization of diverse single-cell data (transcriptomic, epigenomic, proteomic) using affordable VR hardware.
  • To overcome hardware costs and technical expertise barriers in VR-based single-cell data analysis.

Main Methods:

  • Developed singlecellVR, a web application compatible with low-cost VR hardware (e.g., Google Cardboard).
  • Integrated analysis modalities including clustering, trajectory inference, and RNA velocity modeling.
  • Created a companion software package (scvr) for streamlined data conversion from common single-cell analysis tools.

Main Results:

  • SinglecellVR provides accessible visualization for transcriptomic, epigenomic, and proteomic single-cell data.
  • The application supports advanced analyses like clustering and trajectory inference.
  • A companion tool and database facilitate data integration and sharing.

Conclusions:

  • SinglecellVR democratizes VR-based single-cell data visualization.
  • The tool supports diverse data types and advanced analytical methods.
  • It aims to foster wider adoption of VR in single-cell data exploration.