Clinical Application of Dynamic Contrast Enhanced Perfusion Imaging by Cardiovascular Magnetic Resonance

Russell Franks1, Sven Plein1,2, Amedeo Chiribiri1

  • 1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Insights

Cardiovascular magnetic resonance (CMR) perfusion imaging offers a radiation-free method to assess coronary artery disease by evaluating myocardial blood flow. This technique is valuable for diagnosing and managing patients with chronic coronary syndromes.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Radiology

Background:

  • Coronary artery disease (CAD) significantly impacts myocardial blood flow.
  • Non-invasive myocardial perfusion imaging is crucial for detecting CAD.
  • Cardiovascular magnetic resonance (CMR) offers high resolution and avoids ionizing radiation.

Purpose of the Study:

  • To provide an overview of CMR perfusion imaging.
  • To discuss its clinical applications in chronic coronary syndromes.
  • To highlight advancements and challenges in the field.

Main Methods:

  • Dynamic contrast-enhanced CMR perfusion imaging.
  • Assessment of myocardial blood flow.
  • Risk stratification in patients with CAD.

Main Results:

  • CMR perfusion imaging is a validated tool for CAD assessment.
  • It is recommended by international guidelines.
  • Quantitative perfusion analysis is an emerging area.

Conclusions:

  • CMR perfusion imaging is a powerful, non-invasive tool for evaluating CAD.
  • It excels in assessing chronic coronary syndromes.
  • Future directions include advanced quantitative analysis.

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