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Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1

Xiao-Tong Lin1, Hong-Qiang Yu1, Lei Fang1

  • 1Key Laboratory of Hepatobiliary and Pancreatic Surgery, Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.

Elife
|November 15, 2021
PubMed

Keywords:
FBXO45HCCIGF2BP1PLK1biochemistrycancer biologychemical biologyfbxo45hccigf2bp1over survivalplk1targeted therapytumorigenesisubiquitination

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