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Systemic Corticosteroids in Patients With Bronchial Asthma: A Real-Life Study
J L Izquierdo1,2, C Almonacid3, C Campos4
1Department of Medicine and Medical Specialties, University of Alcalá, Madrid, Spain.
Journal of Investigational Allergology & Clinical Immunology
|November 15, 2021
Summary
Systemic corticosteroids (SCs) are frequently prescribed for asthma patients, particularly in primary care settings. This frequent use is linked to increased adverse events, highlighting the need for reduced prescription rates.
Area of Science:
- Pulmonology
- Pharmacology
- Health Informatics
Background:
- Asthma management often involves systemic corticosteroids (SCs).
- Understanding SCs prescription patterns is crucial for patient safety and effective asthma care.
- Big data analytics offers novel insights into real-world medication use.
Purpose of the Study:
- To analyze the utilization of systemic corticosteroids (SCs) in bronchial asthma patients.
- To identify trends and patterns in SC prescription using big data.
Main Methods:
- An observational, retrospective study utilizing electronic health record data from Spain.
- Big data and artificial intelligence (AI) were employed for analysis.
- Analysis included 103,667 asthma patients aged 10-90 years.
Main Results:
- Over 58,000 asthma patients received SCs during the study period.
- SCs were frequently prescribed, with usage increasing from 31.4% in 2015 to 39.6% in 2019.
- Primary care physicians were the main prescribers (59%), and SC use correlated with adverse effects.
Conclusions:
- Systemic corticosteroids are commonly prescribed for asthma, especially in primary care.
- Increased SC prescription is associated with a higher incidence of adverse events.
- Strategies to decrease SC prescribing in asthma patients, particularly in primary care, are warranted.
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