Photodegradation of chloramphenicol in micro-polluted water using a circulatory thin-layer inclined plate reactor

This study describes the photodegradation of chloramphenicol (CAP) in micro-polluted water with a thin-layer inclined plate reactor. Under simulated sunlight irradiation, the effect of reaction parameters including solution pH, initial CAP concentration, and co-existed humic acid (HA) or chloride was evaluated. The photodegradation of CAP was independent of initial pH in the range of 6.0-9.0, but sharply decreased by 25.5% with the increase of initial CAP concentration from 0.4 to 1.0 mg/L. The presence of HA exhibited a significant inhibitory effect, while Cl^- promoted the photoreaction. In this study, CAP was degraded through both direct and indirect photolysis, in which ¹O₂ was the main reactive species responsible for the indirect route. Its steady-state concentration in the micro-polluted water was determined to be 1.40 × 10^-13 mol/L. Transformation intermediates were identified to propose the degradation pathway of CAP, which substantially met the density functional theory (DFT) calculation results. Moreover, four other pharmaceuticals including tetracycline, doxycycline, oxytetracycline, and minocycline were also successfully photodegraded during 5 h irradiation. Therefore, the designed circulatory thin-layer inclined plate reactor is suggested to be effectively applied to the decontamination of organic micro-polluted water.