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Case Report: Dengue Hemorrhagic Fever with Ischemic Stroke
Basnayake Wasala Mudiyanselage Kumarini Eranthika Basnayake1, Kaluachchi Gamage Samanthi Kumari Somaratne1, Chathuri Udeshika Goonetilleke1
1Colombo North Teaching Hospital, Ragama, Sri Lanka.
The American Journal of Tropical Medicine and Hygiene
|November 15, 2021
Summary
This case report details a rare instance of ischemic stroke in a patient with dengue hemorrhagic fever. The study highlights the unusual presentation of dengue, emphasizing the need for further research into its neurological complications.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Medicine
Background:
- Dengue infection can present with various neurological complications, though stroke is exceptionally rare.
- Hemorrhagic strokes are more commonly associated with dengue, primarily due to thrombocytopenia.
Observation:
- A 52-year-old male with dengue hemorrhagic fever developed sudden left-sided weakness and numbness.
- MRI confirmed a right thalamic lacunar infarct, indicating an ischemic stroke.
- Diagnosis was supported by leuko-thrombocytopenia, positive dengue nonstructural protein-1 (NS-1) antigen, and IgM antibodies.
Findings:
- The patient experienced an ischemic stroke during the critical phase of dengue hemorrhagic fever.
- Neurological symptoms and disability showed good recovery upon discharge.
- This case adds to the limited evidence of ischemic stroke as a dengue complication.
Implications:
- This case underscores the potential for ischemic stroke in dengue patients, a phenomenon less documented than hemorrhagic stroke.
- Further research is warranted to elucidate the pathogenic mechanisms linking dengue infection to ischemic stroke.
- Clinicians should consider dengue as a potential cause of stroke, even in its ischemic form.
