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Identification and Mapping Real-World Data Sources for Heart Failure, Acute Coronary Syndrome, and Atrial
Rachel Studer1, Claudio Sartini2, Kiliana Suzart-Woischnik2
1Novartis Pharma AG, Novartis Campus, Basel, Switzerland.
Cardiology
|November 15, 2021
Summary
This review identified global real-world data sources for heart failure, acute coronary syndrome, and atrial fibrillation. The comprehensive resource aids future cardiovascular research and patient outcomes.
Area of Science:
- Cardiovascular medicine
- Health informatics
- Epidemiology
Background:
- Real-world data (RWD) is crucial for global health, particularly for cardiovascular diseases.
- This study aimed to identify global RWD sources for heart failure (HF), acute coronary syndrome (ACS), and atrial fibrillation (AF).
Approach:
- A systematic review of publications (2010-2018) related to HF, ACS, and AF was conducted.
- Metadata on data source type, study design, population, clinical characteristics, follow-up, outcomes, and data availability were extracted.
Key Points:
- Over 322 (HF), 287 (ACS), and 220 (AF) unique RWD sources were identified from thousands of publications.
- Demographic and comorbidity data were widely available, but drug codes and caregiver involvement were sparsely reported.
- Limited information was available on data accessibility for researchers (11%) and data linkage potential (20%).
Conclusions:
- A comprehensive resource of cardiovascular RWD sources was created.
- This resource offers new opportunities to enhance real-world research in cardiovascular diseases.
- The findings aim to contribute to achieving better patient outcomes through improved research.
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