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Updated: Oct 13, 2025

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts
Published on: August 26, 2021
Heartbeat instability as auto-oscillation between dim and bright void regimes
A Pikalev1, M Pustylnik1, C Räth1
1Institut für Materialphysik im Weltraum, Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR), 82234 Weßling, Germany.
Abstract:
We investigated the self-excited as well as optogalvanically stimulated heartbeat instability in RF discharge complex plasma. Three video cameras measured the motion of the microparticles, the plasma emission, and the laser-induced fluorescence simultaneously. Comprehensive studies of the optogalvanic control of the heartbeat instability revealed that the microparticle suspension can be stabilized by a continuous laser, whereas a modulated laser beam induces the void contraction either transiently or resonantly. The resonance occurred when the laser modulation frequency coincided with the frequency of small breathing oscillations of the microparticle suspension, which are known to be a prerequisite to the heartbeat instability. Based on the experimental results we suggest that the void contraction during the instability is caused by an abrupt void transition from the dim to the bright regime [Pikalev et al., Plasma Sources Sci. Technol. 30, 035014 (2021)PSTEEU0963-025210.1088/1361-6595/abe0a2]. In the bright regime, a time-averaged electric field at the void boundary heats the electrons causing bright plasma emission inside the void. The dim void has much lower electric field at the boundary and exhibits therefore no emission feature associated with it.
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