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AIE-MOF materials for biological applications
Tahir Mehmood1, J Prakasha Reddy1
1Department of Chemistry, School of Sciences, Indrashil University, Rajpur, Gujarat, India.
Progress in Molecular Biology and Translational Science
|November 16, 2021
Summary
This chapter reviews recent advancements in aggregation-induced emission Metal-Organic Frameworks (AIE-MOFs). It highlights their synthesis and biological applications, including cell imaging and drug delivery.
Area of Science:
- Coordination Chemistry
- Materials Science
- Biotechnology
Background:
- Metal-Organic Frameworks (MOFs) are highly porous, crystalline materials with tunable properties.
- Aggregation-Induced Emission (AIE) is a phenomenon with significant potential in biological applications.
- AIE-MOFs combine the structural advantages of MOFs with the unique optical properties of AIE materials.
Purpose of the Study:
- To provide a focused overview of recent developments in AIE-MOFs.
- To summarize the synthesis strategies for AIE-MOFs.
- To highlight current and emerging biological applications of AIE-MOFs.
Main Methods:
- Literature review of recent research on AIE-MOFs.
- Analysis of synthesis methodologies for creating AIE-MOFs.
- Categorization of biological applications based on published studies.
Main Results:
- AIE-MOFs have demonstrated promise in various biological applications.
- Key synthesis approaches for AIE-MOFs have been identified.
- Specific applications discussed include cell imaging, heparin detection, and drug delivery.
Conclusions:
- AIE-MOFs represent a rapidly developing field with significant potential in biomedicine.
- Further research is needed to overcome challenges and fully realize the prospects of AIE-MOFs.
- This review provides a foundation for future investigations into AIE-MOF materials.

