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Updated: Oct 13, 2025

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

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[Physiological and pathological responses to altitude].

¹Inserm, UM sports et pathologies, laboratoire HP2, CHU Grenoble-Alpes, université Grenoble Alpes, EXALT - centre d'expertise sur l'altitude, 38000 Grenoble, France.

Revue Des Maladies Respiratoires

|November 16, 2021

Summary

This summary is machine-generated.

High altitude exposure causes physiological changes affecting the cardiovascular and respiratory systems. Individual responses vary, leading to conditions like acute mountain sickness and high-altitude edema.

Keywords:

Acute mountain sickness Altitude Cœur Heart Hypoxia Hypoxie Mal aigu des montagnes Poumons lungs.

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Last Updated: Oct 13, 2025

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Area of Science:

Physiology
Altitude Medicine

Background:

High altitude environments present hypobaric hypoxia, impacting oxygen balance.
Acclimatization to altitude is complex and highly individual.

Purpose of the Study:

To review current knowledge on high-altitude acclimatization.
To discuss diseases associated with high-altitude exposure.

Main Methods:

Literature review of physiological responses to altitude.
Synthesis of information on acclimatization and altitude illnesses.

Main Results:

Hypobaric hypoxia necessitates physiological adjustments in cardiovascular and respiratory systems.
Individual variability in acclimatization leads to a spectrum of responses.
Non-specific symptoms characterize acute mountain sickness and high-altitude edema.

Conclusions:

Understanding acclimatization is crucial for managing high-altitude physiology.
Knowledge of altitude-related diseases is essential for prevention and treatment.