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Updated: Oct 13, 2025

Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion
Published on: February 22, 2013
Central Retinal Artery Visualization with Cone-Beam CT Angiography.
Eytan Raz1, Maksim Shapiro1, Timothy M Shepherd1
1From the Departments of Radiology (E.R., M.S., T.M.S., O.M., M.H., M.G.Y., P.K.N.), Neurology (M.S., S.Y., D.M.G., K.I., J.C.R., S.A., S.L.G.), Neurosurgery (E.N., P.K.N.), and Ophthalmology (J.C.R., I.B., E.K., S.L.G.), Bernard and Irene Schwartz Neurointerventional Section (E.R., M.S., P.K.N.), NYU Langone Health, 660 First Ave, 7th Floor, New York, NY 10016; Department of Neurology, Brown University, Providence, RI (S.Y.); and Department of Neurology, Duke University School of Medicine, Durham, NC (B.M.G.).
Cone-beam CT (CBCT) successfully visualized the central retinal artery (CRA) in vivo during cerebral angiography. This technique offers a reliable method for imaging the CRA
Area of Science:
- Ophthalmology
- Radiology
- Medical Imaging
Background:
- Existing imaging techniques struggle to visualize the entire retrobulbar course of retinal and ciliary vessels in vivo.
- There is a need for reliable in vivo imaging of the retrobulbar vasculature.
Purpose of the Study:
- To identify and characterize the central retinal artery (CRA) using cone-beam CT (CBCT).
- To evaluate CBCT's utility for visualizing the CRA's retrobulbar course.
Main Methods:
- Retrospective analysis of CBCT angiography data from patients undergoing cerebral angiography.
- Data included orbits within the field of view, postprocessed to 0.2 mm resolution.
- Evaluated CRA origin, course, optic nerve penetration, bifurcation, variants, and central retinal vein visualization.
Main Results:
- The central retinal artery (CRA) was identified in all 24 visualized orbits.
- CRA origin, course, optic nerve penetration, and termination were consistently visualized.
- The central retinal vein was visualized in 6 of 24 orbits.
Conclusions:
- Cone-beam CT (CBCT) reliably demonstrates the in vivo central retinal artery.
- CBCT shows significant potential for various diagnostic and therapeutic applications in ophthalmology.
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