[Prediction of spontaneous abortion by vaginal cytologic smears (author's transl)i1]

Vaginal smears were obtained from 175 women during the first four months of pregnancy weekly and the Karyopycnotic Index and the Eosinophilic Index encountered by phase contrast microscopy. The normal values were listed our by percentils. The development of KPI and Eo I during early pregnancy were compaired in three groups of patients: 1, 120 women with normal early pregnancy, 2.20 women with threatened abortion but good following up of later pregnancy, and 3. 35 women with spontaneous abortion. Even 4 weeks before abortion vaginal smears changed to pathological values in about 40% of all patients with spontaneous abortion. Women with threatened abortion but good outcome of pregnancy used to have normal KPI and Eo I.