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Related Experiment Video

Updated: Oct 13, 2025

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
05:35

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

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Developments in optimizing transperineal prostate biopsy.

Emily Cheng1, Meenakshi Davuluri, Patrick J Lewicki

  • 1Department of Urology, NewYork Presbyterian Hospital/Weil Cornell Medicine, New York, New York, USA.

Current Opinion in Urology
|November 16, 2021
PubMed
Summary
This summary is machine-generated.

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Transperineal prostate biopsy offers a safer alternative to transrectal biopsy, reducing infection risks and potentially eliminating the need for antibiotics. This approach optimizes prostate cancer diagnosis and surveillance with significant healthcare savings.

Area of Science:

  • Urology
  • Oncology
  • Minimally Invasive Procedures

Background:

  • Prostate biopsy is crucial for diagnosing prostate cancer, the most common male malignancy.
  • Transrectal biopsy is the standard, but carries infection risks.
  • Transperineal biopsy offers a percutaneous, lower-infection-risk alternative.

Purpose of the Study:

  • To review emerging developments in transperineal prostate biopsy.
  • To discuss how these advancements can optimize clinical practice.
  • To highlight the advantages of transperineal over transrectal biopsy.

Main Methods:

  • Systematic and MRI-targeted biopsy cores can be performed with the transperineal approach.
  • Procedures can be performed freehand under local anesthesia or sedation, avoiding general anesthesia.

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  • Eliminates the translocation of rectal bacteria, reducing infection risk.

    • Main Results:

    • Transperineal biopsy significantly decreases infection risk compared to transrectal biopsy.
    • Feasibility of forgoing peri-procedural antibiotics, potentially reducing antimicrobial resistance.
    • Potential for significant healthcare savings by reducing infections and hospitalizations.

    Conclusions:

    • Transperineal biopsy with MRI-targeting offers advantages over traditional transrectal methods.
    • Performing transperineal biopsy under local anesthesia without antibiotics is a promising approach for prostate cancer diagnosis and surveillance.