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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

961
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
961
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

886
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
886
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

748
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
748

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Updated: Oct 13, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Structure-function analysis for macular surgery in patients with coexisting glaucoma.

Sarah N Yu1, Donald C Hood1,2, Dana M Blumberg1

  • 1Department of Ophthalmology, Columbia University, New York, NY, USA.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|November 16, 2021
PubMed
Summary
This summary is machine-generated.

Assessing pre-operative retinal structure and function in glaucoma patients with epiretinal membranes or macular holes is crucial. This aids surgical planning and outcome evaluation for better vision restoration.

Keywords:
Epiretinal membraneGlaucomaMacular holeOptical coherence tomographyVisual field

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Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Glaucoma Research

Background:

  • Epiretinal membranes (ERM) and macular holes (MH) can coexist with glaucoma, complicating visual field assessment.
  • Glaucomatous damage can affect retinal structure and function, making surgical planning challenging.

Purpose of the Study:

  • To develop methods for assessing pre-operative retinal structure and function in eyes with coexisting glaucoma, ERM, or MH.
  • To evaluate post-operative outcomes following macular surgery in these patients.

Main Methods:

  • Seven eyes with glaucoma and either ERM or MH underwent evaluation.
  • Pre- and post-operative visual fields (VFs) and optical coherence tomography (OCT) scans were analyzed.
  • OCT data (ganglion cell-inner plexiform layer, retinal nerve fiber layer) were correlated with VF deviation maps.

Main Results:

  • Pre-operative analysis highlighted the need to differentiate glaucomatous damage from other causes of VF loss.
  • Automated segmentation of retinal layers and foveal anatomy assessment were important.
  • Post-operative evaluation required adjustments for OCT magnification and careful follow-up to interpret VF changes.

Conclusions:

  • Pre-operative comparison of VFs and OCT is valuable for surgical planning in glaucoma patients undergoing macular surgery.
  • This approach aids in predicting and evaluating surgical outcomes.