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Related Experiment Video

Updated: Oct 13, 2025

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Recent Advances in Bioinspired Hydrogels: Materials, Devices, and Biosignal Computing.

Yangzhi Zhu1, Reihaneh Haghniaz1, Martin C Hartel1,2

  • 1Terasaki Institute for Biomedical Innovation, Los Angeles, California 90064, United States.

ACS Biomaterials Science & Engineering
|November 16, 2021
PubMed
Summary

Bioinspired hydrogel wearable devices mimic biological systems for advanced sensing and adaptation. This review explores their development, applications like electronic skin, and future potential in seamless human-device integration.

Keywords:
bioinspired hydrogelsbiosensorsbiosignal computingdiagnosticsflexible electronicswearable devices

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Area of Science:

  • Biomaterials Science
  • Wearable Technology
  • Bioinspired Engineering

Background:

  • Biological systems exhibit remarkable environmental sensing and adaptation.
  • Hydrogels offer unique properties like softness, biocompatibility, and stimulus responsiveness for wearable devices.
  • Bioinspired materials are crucial for next-generation wearable technologies.

Purpose of the Study:

  • To review recent strategies for developing bioinspired hydrogel wearable devices.
  • To highlight advancements in hydrogel materials for accommodating mechanical strain and biological integration.
  • To summarize progress in biosignal readout, powering, and data transmission for these devices.

Main Methods:

  • Review of current literature on bioinspired hydrogels for wearable devices.
  • Analysis of different hydrogel types and their tailored applications.
  • Examination of recent developments in electronic skin and smart contact lenses.
  • Summary of biosignal detection, powering, and wireless data transmission techniques.

Main Results:

  • Diverse bioinspired hydrogels are being developed for enhanced mechanical strain accommodation and biological integration.
  • Significant progress has been made in applications such as electronic skin and smart contact lenses.
  • Advancements in biosignal readout, powering, and wireless data transmission are enabling sophisticated hydrogel wearable devices.

Conclusions:

  • Bioinspired hydrogel wearable devices represent a promising frontier in human-integrated technology.
  • Further research is needed to address current challenges and unlock the full potential of these advanced materials.
  • Future directions include improved device performance, seamless integration, and expanded applications.