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Updated: Oct 13, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
COVID-19-related skin manifestations: Update on therapy
Laura Atzori1, Sebastiano Recalcati2, Caterina Ferreli1
1Dermatology Clinic, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Abstract:
An increasing body of evidence has been produced in a very limited period to improve the understanding of skin involvement in the current coronavirus 2019 disease pandemic, and how this novel disease affects the management of dermatologic patients. A little explored area is represented by the therapeutic approach adopted for the different skin manifestations associated with the infection. An overview of the current scenario is provided, through review of the English-language literature published until October 30, 2020, and comparison with the personal experience of the authors. As dermatologists, our primary aim is to support patients with the highest standard of care and relieve suffering, even with lesions not life-threatening. With asymptomatic COVID-19 patients, patient discomfort related to skin lesions should not be undervalued and intervention to accelerate healing should be provided. Consensus protocols are warranted to assess the best skin-targeted treatments in COVID-19 patients.
Insights
Skin manifestations in coronavirus disease 2019 (COVID-19) require attention, even in asymptomatic patients. Dermatologists should provide care for skin lesions to relieve patient suffering and accelerate healing.
Area of Science:
- Dermatology
- Infectious Diseases
- Public Health
Background:
- The coronavirus disease 2019 (COVID-19) pandemic has highlighted the need to understand its dermatological manifestations.
- Management of dermatologic patients during the pandemic presents unique challenges.
- Therapeutic approaches for COVID-19-associated skin conditions are not well-established.
Purpose of the Study:
- To review the current literature on skin involvement in COVID-19.
- To discuss therapeutic strategies for dermatologic manifestations of COVID-19.
- To provide guidance for dermatologists managing these patients.
Main Methods:
- Literature review of English-language publications up to October 30, 2020.
- Synthesis of findings with authors' clinical experience.
Main Results:
- Evidence on COVID-19's skin manifestations has rapidly increased.
- Skin lesions can occur in both symptomatic and asymptomatic COVID-19 patients.
- Patient discomfort from skin lesions, even non-life-threatening, should be addressed.
Conclusions:
- Dermatologists must provide optimal care for all COVID-19 patients with skin conditions.
- Interventions to accelerate healing of skin lesions are important, even in asymptomatic cases.
- Consensus protocols are needed for effective skin-targeted treatments in COVID-19.
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