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Updated: Oct 13, 2025

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
The selective detection of Fe3+ ions using citrate-capped gold nanoparticles
Xinhua Meng1, Bijing Lei1, Na Qi1
1Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400030, China.
Abstract:
Citrate is a ubiquitous biological molecule that functions as Fe3+ chelators in some bacteria and the blood plasma of humans. Inspired by the strong affinity between citrate and Fe3+, a colorimetric Fe3+ probe based on citrate-capped AuNPs without any additional modification was designed. Citrate-capped AuNPs with a diameter of 22 nm were applied to detect Fe3+ without other reagents' assistance. This easily-prepared and low-cost colorimetric sensor exhibited good selectivity towards Fe3+ among common metal ions, a good linear relationship in the range of 0.1-0.8 μM of Fe3+ and quick response time of 10 min.
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