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Stereotactic Radiosurgery for Incidentally Discovered Cavernous Sinus Meningiomas: A Multi-institutional Study
Stylianos Pikis1, Georgios Mantziaris1, Yavuz Samanci2
1Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA.
World Neurosurgery
|November 17, 2021
Summary
Stereotactic radiosurgery (SRS) is a safe and effective treatment for asymptomatic cavernous sinus (CS) meningiomas. Consider SRS at diagnosis or if tumor growth is observed during follow-up.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Management of asymptomatic cavernous sinus (CS) meningiomas is not well-defined.
- Incidental discovery of CS meningiomas necessitates treatment evaluation.
- Stereotactic radiosurgery (SRS) is a potential treatment modality.
Purpose of the Study:
- To evaluate the safety and efficacy of upfront SRS for asymptomatic CS meningiomas.
- To assess local tumor control and complication rates.
- To determine the incidence of new neurological deficits post-SRS.
Main Methods:
- International, retrospective study design.
- Inclusion of patients with asymptomatic CS meningiomas treated with upfront SRS.
- Evaluation of tumor control, complications, and neurological outcomes.
Main Results:
- 37 patients (29 male, mean age 55.05 years) were included.
- Tumor regression (51.35%) and stability (48.65%) were observed.
- Low complication rate (5.4%) managed conservatively.
Conclusions:
- Upfront SRS is a safe and effective option for asymptomatic CS meningiomas.
- SRS can be considered at initial diagnosis.
- SRS is recommended for growing CS meningiomas during observation.
